I dont know what the issue is. The only thing I find questionable is what RedAlertRiker points out: How does it effect the child when the "mother" takes or has taken hormones? I dont know what medicine says about this.
Everything else is not a problem at all. How will he breast fead the child? Not at all, I guess.
And its not the genome, that is of interest in such a case, but the whomp. If its still there, then he is technically spoken still a women. Thats what most people misinterprete when talking of a sex change. Its a plastic surgery thing for the most part. Its not really a change of sex, thats not what is most important for this people, its a change of gender.
Its important for transgender people to be seen and to feel like the opposite gender (whatever that means for the individual).