I don't think other humanoids are particularly unlikely. Evolution works by favouring the type of life best suited to a particular environment. If another world goes through the same environments that produced us great apes in just one of its regions (and considering the size of the 'verse, law of averages says there must be some), you're not going to get a many tentacled land octopus with wings. It's gonna be something at least vaguely similar to us.
And considering you need opposable thumbs to create tools, you need at least two eyes for depth perception, ect, ect, any advanced races will be more similar to us then dissimilar.